Species specificity of amidine-based urokinase inhibitors.

Klinghofer, V; Stewart, K; McGonigal, T; Smith, R; Sarthy, A; Nienaber, V; Butler, C; Dorwin, S; Richardson, P; Weitzberg, M; Wendt, M; Rockway, T; Zhao, X; Hulkower, K I; Giranda, V L

Klinghofer, V; Stewart, K; McGonigal, T; Smith, R; Sarthy, A; Nienaber, V; Butler, C; Dorwin, S; Richardson, P; Weitzberg, M; Wendt, M; Rockway, T; Zhao, X; Hulkower, K I; Giranda, V L.

Affiliation

Klinghofer V; Department of Cancer Research, Abbott Laboratories, Abbott Park, Illinois 60064-6117, USA. vered.klinghofer@abbott.com

Biochemistry ; 40(31): 9125-31, 2001 Aug 07.

Article in En | MEDLINE | ID: mdl-11478879

Subject(s)

Amidines/chemistry; Serine Proteinase Inhibitors/chemistry; Urokinase-Type Plasminogen Activator/antagonists & inhibitors; Amidines/chemical synthesis; Amiloride/chemical synthesis; Amino Acid Sequence; Animals; Antineoplastic Agents/chemical synthesis; Binding Sites; Blood Proteins; Carcinoma, Lewis Lung; Crystallography, X-Ray; Humans; Mice; Molecular Sequence Data; Naphthalenes/chemical synthesis; Sequence Alignment; Sequence Homology, Amino Acid; Serine Proteinase Inhibitors/chemical synthesis; Species Specificity; Thiophenes/chemical synthesis; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Urokinase-Type Plasminogen Activator / Serine Proteinase Inhibitors / Amidines Limits: Animals / Humans Language: En Journal: Biochemistry Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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