Lack of complex I activity in human cells carrying a mutation in MtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene.

Bai, Y; Hájek, P; Chomyn, A; Chan, E; Seo, B B; Matsuno-Yagi, A; Yagi, T; Attardi, G

Bai, Y; Hájek, P; Chomyn, A; Chan, E; Seo, B B; Matsuno-Yagi, A; Yagi, T; Attardi, G.

Affiliation

Bai Y; Division of Biology 156-29, California Institute of Technology, Pasadena, California 91125, USA.

J Biol Chem ; 276(42): 38808-13, 2001 Oct 19.

Article in En | MEDLINE | ID: mdl-11479321

Subject(s)

DNA, Mitochondrial/genetics; Mutation; Quinone Reductases/genetics; Saccharomyces cerevisiae/enzymology; Saccharomyces cerevisiae/genetics; Binding Sites; Cell Division; Cell Line; Cell Nucleus/enzymology; Electrophoresis, Polyacrylamide Gel; Frameshift Mutation; Glucose/metabolism; Humans; Microscopy, Confocal; Mitochondria/metabolism; NAD/metabolism; Oxygen/metabolism; Oxygen Consumption; Protein Binding; Quinone Reductases/metabolism; RNA, Messenger/metabolism; Time Factors; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Quinone Reductases / Saccharomyces cerevisiae / DNA, Mitochondrial / Mutation Limits: Humans Language: En Journal: J Biol Chem Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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