Cyclooxygenase-2 mediates the febrile response of mice to interleukin-1beta.

Li, S; Ballou, L R; Morham, S G; Blatteis, C M

Li, S; Ballou, L R; Morham, S G; Blatteis, C M.

Affiliation

Li S; Department of Physiology, University of Tennessee Health Science Center (UTHSC), 894 Union Avenue, Memphis, TN 38163, USA.

Brain Res ; 910(1-2): 163-73, 2001 Aug 10.

Article in En | MEDLINE | ID: mdl-11489266

Subject(s)

Brain/drug effects; Dinoprostone/metabolism; Fever/enzymology; Interleukin-1/pharmacology; Isoenzymes/metabolism; Peptide Fragments/pharmacology; Prostaglandin-Endoperoxide Synthases/metabolism; Pyrogens/metabolism; Animals; Body Temperature/drug effects; Body Temperature/physiology; Brain/enzymology; Cyclooxygenase 1; Cyclooxygenase 2; Fever/chemically induced; Fever/physiopathology; Inflammation/metabolism; Inflammation/physiopathology; Injections, Intraventricular; Interleukin-1/metabolism; Interleukin-1beta; Isoenzymes/antagonists & inhibitors; Isoenzymes/genetics; Lipopolysaccharides/metabolism; Lipopolysaccharides/pharmacology; Membrane Proteins; Mice; Mice, Knockout; Neuroimmunomodulation/drug effects; Neuroimmunomodulation/physiology; Peptide Fragments/metabolism; Prostaglandin-Endoperoxide Synthases/genetics; Pyrogens/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Pyrogens / Brain / Dinoprostone / Interleukin-1 / Prostaglandin-Endoperoxide Synthases / Fever / Isoenzymes Limits: Animals Language: En Journal: Brain Res Year: 2001 Document type: Article Affiliation country: United States Country of publication: Netherlands

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