Determination of the extracellular concentration of glycine in the rat spinal cord dorsal horn by quantitative microdialysis.
Brain Res
; 910(1-2): 192-4, 2001 Aug 10.
Article
in En
| MEDLINE
| ID: mdl-11489271
ABSTRACT
Two quantitative microdialysis methods were used to determine the extracellular concentration of glycine in the dorsal spinal cord of halothane-anaesthetised rats. Extracellular glycine determined by zero net flux was 2.6+/-0.3 microM and by the zero flow method was 3.3+/-0.3 microM. For comparison the glycine content of cerebrospinal fluid was determined to be 6.4+/-1.1 microM. There was no correlation between the extracellular and the cerebrospinal fluid concentrations.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Receptors, N-Methyl-D-Aspartate
/
Microdialysis
/
Synaptic Transmission
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Posterior Horn Cells
/
Extracellular Space
/
Glycine
Limits:
Animals
Language:
En
Journal:
Brain Res
Year:
2001
Document type:
Article
Affiliation country:
United kingdom