Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase.

Hadjur, S; Ung, K; Wadsworth, L; Dimmick, J; Rajcan-Separovic, E; Scott, R W; Buchwald, M; Jirik, F R

Hadjur, S; Ung, K; Wadsworth, L; Dimmick, J; Rajcan-Separovic, E; Scott, R W; Buchwald, M; Jirik, F R.

Affiliation

Hadjur S; Centre for Molecular Medicine and Therapeutics, British Columbia Research Institute for Children's and Women's Health, University of British Columbia, Vancouver, British Columbia, Canada.

Blood ; 98(4): 1003-11, 2001 Aug 15.

Article in En | MEDLINE | ID: mdl-11493445

Subject(s)

Cell Cycle Proteins; DNA-Binding Proteins; Fatty Liver/genetics; Hematopoiesis/genetics; Nuclear Proteins; Proteins/genetics; Superoxide Dismutase/genetics; Animals; Bone Marrow Cells/pathology; Bone Marrow Diseases/pathology; Disease Models, Animal; Erythrocyte Count; Erythrocytes/pathology; Fanconi Anemia/complications; Fanconi Anemia/pathology; Fanconi Anemia Complementation Group C Protein; Fanconi Anemia Complementation Group Proteins; Fatty Liver/complications; Leukopenia/etiology; Leukopenia/genetics; Mice; Mice, Knockout; Oxidation-Reduction; Proteins/pharmacology; Superoxide Dismutase/deficiency; Superoxide Dismutase/pharmacology; Superoxides/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Superoxide Dismutase / Nuclear Proteins / Proteins / Cell Cycle Proteins / DNA-Binding Proteins / Fatty Liver / Hematopoiesis Type of study: Etiology_studies Limits: Animals Language: En Journal: Blood Year: 2001 Document type: Article Affiliation country: Canada Country of publication: United States

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