Induction therapy with monoclonal antibodies specific for CD80 and CD86 delays the onset of acute renal allograft rejection in non-human primates.

Kirk, A D; Tadaki, D K; Celniker, A; Batty, D S; Berning, J D; Colonna, J O; Cruzata, F; Elster, E A; Gray, G S; Kampen, R L; Patterson, N B; Szklut, P; Swanson, J; Xu, H; Harlan, D M

Kirk, A D; Tadaki, D K; Celniker, A; Batty, D S; Berning, J D; Colonna, J O; Cruzata, F; Elster, E A; Gray, G S; Kampen, R L; Patterson, N B; Szklut, P; Swanson, J; Xu, H; Harlan, D M.

Affiliation

Kirk AD; NIDDK/Navy-Transplantation and Autoimmunity Branch, 8901 Wisconsin Avenue, Bethesda, MD 20889, USA.

Transplantation ; 72(3): 377-84, 2001 Aug 15.

Article in En | MEDLINE | ID: mdl-11502964

Subject(s)

Antibodies, Monoclonal/immunology; Antibodies, Monoclonal/therapeutic use; Antigens, CD/immunology; B7-1 Antigen/immunology; Graft Rejection/prevention & control; Kidney Transplantation; Membrane Glycoproteins/immunology; Acute Disease; Animals; Antibody Formation/drug effects; B7-2 Antigen; Dendritic Cells/pathology; Drug Therapy, Combination; Graft Rejection/genetics; Humans; Kidney/pathology; Lymphocyte Culture Test, Mixed; Lymphocytes/pathology; Macaca mulatta; RNA/analysis; Safety; Tissue Donors; Transplantation, Homologous

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Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Antigens, CD / Kidney Transplantation / B7-1 Antigen / Graft Rejection / Antibodies, Monoclonal Limits: Animals / Humans Language: En Journal: Transplantation Year: 2001 Document type: Article Affiliation country: United States

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