Eradication of intraperitoneal and distant tumor by adenovirus-mediated interferon-beta gene therapy is attributable to induction of systemic immunity.

Odaka, M; Sterman, D H; Wiewrodt, R; Zhang, Y; Kiefer, M; Amin, K M; Gao, G P; Wilson, J M; Barsoum, J; Kaiser, L R; Albelda, S M

Odaka, M; Sterman, D H; Wiewrodt, R; Zhang, Y; Kiefer, M; Amin, K M; Gao, G P; Wilson, J M; Barsoum, J; Kaiser, L R; Albelda, S M.

Affiliation

Odaka M; Thoracic Oncology Research Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA.

Cancer Res ; 61(16): 6201-12, 2001 Aug 15.

Article in En | MEDLINE | ID: mdl-11507073

Subject(s)

Genetic Therapy/methods; Interferon-beta/genetics; Interferon-beta/immunology; Mesothelioma/therapy; Peritoneal Neoplasms/therapy; Adenoviridae/genetics; Animals; CD4-Positive T-Lymphocytes/immunology; Cell Division/immunology; Cytotoxicity, Immunologic; Dose-Response Relationship, Immunologic; Female; Genetic Vectors/genetics; Injections, Intraperitoneal; Interferon-beta/metabolism; Mesothelioma/genetics; Mesothelioma/immunology; Mice; Mice, Inbred BALB C; Mice, SCID; Peritoneal Neoplasms/genetics; Peritoneal Neoplasms/immunology; T-Lymphocytes, Cytotoxic/immunology; Transfection

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Peritoneal Neoplasms / Genetic Therapy / Interferon-beta / Mesothelioma Limits: Animals Language: En Journal: Cancer Res Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links