Differential gene expression in response to methoxychlor and estradiol through ERalpha, ERbeta, and AR in reproductive tissues of female mice.

Waters, K M; Safe, S; Gaido, K W

Waters, K M; Safe, S; Gaido, K W.

Affiliation

Waters KM; Department of Endocrine, Reproductive and Developmental Toxicology, CIIT Centers for Health Research, 6 Davis Drive, Research Triangle Park, North Carolina 27709, USA.

Toxicol Sci ; 63(1): 47-56, 2001 Sep.

Article in En | MEDLINE | ID: mdl-11509743

Subject(s)

Estradiol/toxicity; Gene Expression Regulation/drug effects; Genitalia, Female/drug effects; Methoxychlor/metabolism; Receptors, Androgen/metabolism; Receptors, Estrogen/metabolism; Animals; DNA Primers/chemistry; Drug Combinations; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Flutamide/toxicity; Genitalia, Female/metabolism; Mice; Mice, Inbred C57BL; Ovary/drug effects; Ovary/metabolism; Phenols/toxicity; RNA, Messenger/metabolism; Receptors, Androgen/genetics; Receptors, Estrogen/genetics; Reverse Transcriptase Polymerase Chain Reaction; Uterus/drug effects; Uterus/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Androgen / Receptors, Estrogen / Gene Expression Regulation / Estradiol / Genitalia, Female / Methoxychlor Limits: Animals Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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