Hypoglycemia associated with the production of insulin-like growth factor II in adrenocortical carcinoma.
Intern Med
; 40(8): 759-63, 2001 Aug.
Article
in En
| MEDLINE
| ID: mdl-11518119
A 78-year-old woman was hospitalized for congestive heart failure and repeated hypoglycemic attacks. The laboratory data showed a serum insulin level within the normal range and an increased level of serum insulin-like growth factor (IGF) II. Abdominal ultrasonogram and computed tomography scan revealed a huge mass lying above the left kidney. She was diagnosed as having an adrenocortical carcinoma. After the removal of the tumor, the plasma glucose level and the serum level of IGF-II were normalized. The tumor cells stained positively for IGF-II immunohistochemically. These findings suggested that the hypoglycemia was due to IGF-II produced by the adrenocortical carcinoma.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Insulin-Like Growth Factor II
/
Adrenal Cortex Neoplasms
/
Adrenocortical Carcinoma
/
Hypoglycemia
Type of study:
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
Language:
En
Journal:
Intern Med
Journal subject:
MEDICINA INTERNA
Year:
2001
Document type:
Article
Country of publication:
Japan