Genotype transposer: automated genotype manipulation for linkage disequilibrium analysis.

ABSTRACT

UNLABELLED The purpose of this work is to provide the modern molecular geneticist with tools to perform more efficient and more accurate analysis of the genotype data they produce. By using Microsoft Excel macros written in Visual Basic, we can translate genotype data into a form readable by the versatile software 'Arlequin', read the Arlequin output, calculate statistics of linkage disequilibrium, and put the results in a format for viewing with the software 'GOLD'. AVAILABILITY: The software is available by FTP at ftp//xcsg.iarc.fr/cox/Genotype_Transposer/. SUPPLEMENTARY INFORMATION Detailed instruction and examples are available at ftp//xcsg.iarc.fr/cox/Genotype&_Transposer/. Arlequin is available at http//lgb.unige.ch/arlequin/. GOLD is available at http//www.well.ox.ac.uk/asthma/GOLD/.