Caspase 3 deficiency rescues peripheral nervous system defect in retinoblastoma nullizygous mice.

Simpson, M T; MacLaurin, J G; Xu, D; Ferguson, K L; Vanderluit, J L; Davoli, M A; Roy, S; Nicholson, D W; Robertson, G S; Park, D S; Slack, R S

Simpson, M T; MacLaurin, J G; Xu, D; Ferguson, K L; Vanderluit, J L; Davoli, M A; Roy, S; Nicholson, D W; Robertson, G S; Park, D S; Slack, R S.

Affiliation

Simpson MT; Neuroscience Research Institute, University of Ottawa, Ottawa, Ontario, K1H-8M5, Canada.

J Neurosci ; 21(18): 7089-98, 2001 Sep 15.

Article in En | MEDLINE | ID: mdl-11549719

Subject(s)

Caspases/deficiency; Peripheral Nervous System/physiopathology; Retinoblastoma Protein/deficiency; Amyloid beta-Protein Precursor/metabolism; Animals; Apoptosis; Caspase 3; Caspases/biosynthesis; Caspases/genetics; Central Nervous System/cytology; Central Nervous System/embryology; Central Nervous System/metabolism; Crosses, Genetic; Enzyme Induction/physiology; Fluorescent Dyes; Ganglia, Spinal/cytology; Ganglia, Spinal/embryology; Ganglia, Spinal/metabolism; Gene Expression Regulation, Developmental/physiology; Genotype; In Situ Nick-End Labeling; Mice; Mice, Knockout; Neurons/classification; Neurons/metabolism; Neurons/pathology; Organ Specificity; Peripheral Nervous System/embryology; Peripheral Nervous System/pathology; Retinoblastoma Protein/biosynthesis; Retinoblastoma Protein/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinoblastoma Protein / Peripheral Nervous System / Caspases Limits: Animals Language: En Journal: J Neurosci Year: 2001 Document type: Article Affiliation country: Canada Country of publication: United States

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