Association between idiopathic infantile macrocephaly and autism spectrum disorders.
Lancet
; 358(9283): 726-7, 2001 Sep 01.
Article
in En
| MEDLINE
| ID: mdl-11551582
ABSTRACT
We conducted a case-controlled, catch-up study of a cohort of boys born with macrocephaly in order to determine whether infantile macrocephaly is a risk marker for the later development of autism spectrum disorders. Our results show that infantile macrocephaly was associated with an increased risk of developing autism spectrum disorders (odds ratio 5.44, 95% CI 1.11-52.15; p=0.03). These findings suggest that neurobiological differences during infancy may predict behavioural manifestations of autism spectrum disorders.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skull
/
Autistic Disorder
/
Cephalometry
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Child, preschool
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Lancet
Year:
2001
Document type:
Article