Astrocytes/metabolism; Brain Injuries/metabolism; Cell Communication/physiology; Growth Substances/metabolism; Microglia/metabolism; Nerve Degeneration/metabolism; Neurons/metabolism; Animals; Brain Injuries/pathology; Brain Injuries/physiopathology; Cell Death/drug effects; Cell Death/physiology; Cell Size/drug effects; Cell Size/physiology; Cells, Cultured/drug effects; Cells, Cultured/metabolism; Cells, Cultured/pathology; Culture Media, Conditioned/pharmacology; Dentate Gyrus/drug effects; Dentate Gyrus/metabolism; Dentate Gyrus/pathology; Disease Models, Animal; Down-Regulation/drug effects; Down-Regulation/physiology; Excitatory Amino Acid Agonists/pharmacology; Fluorescein-5-isothiocyanate/pharmacokinetics; Gliosis/metabolism; Gliosis/pathology; Gliosis/physiopathology; Hippocampus/drug effects; Hippocampus/metabolism; Hippocampus/pathology; Lectins/pharmacokinetics; Microglia/drug effects; Microglia/pathology; Microscopy, Confocal; N-Methylaspartate/pharmacology; Nerve Degeneration/chemically induced; Nerve Degeneration/physiopathology; Neurons/drug effects; Neurons/pathology; Neuroprotective Agents/pharmacology; Neurotoxins/pharmacology; Rats; Rats, Wistar; Transforming Growth Factor beta/pharmacology