Induction of the Epstein-Barr virus thymidine kinase gene with concomitant nucleoside antivirals as a therapeutic strategy for Epstein-Barr virus-associated malignancies.

Faller, D V; Mentzer, S J; Perrine, S P

Faller, D V; Mentzer, S J; Perrine, S P.

Affiliation

Faller DV; Cancer Research Center and Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA. dfaller@bu.edu

Curr Opin Oncol ; 13(5): 360-7, 2001 Sep.

Article in En | MEDLINE | ID: mdl-11555713

Subject(s)

Antineoplastic Agents/pharmacology; Antiviral Agents/therapeutic use; Arginine/analogs & derivatives; Arginine/pharmacology; Butyrates/pharmacology; Epstein-Barr Virus Infections/complications; Ganciclovir/therapeutic use; Gene Expression Regulation, Neoplastic; Herpesvirus 4, Human/genetics; Lymphoma, Non-Hodgkin/therapy; Lymphoma, Non-Hodgkin/virology; Thymidine Kinase/biosynthesis; Antineoplastic Agents/therapeutic use; Arginine/therapeutic use; Butyrates/therapeutic use; Clinical Trials as Topic; Combined Modality Therapy; Enzyme Induction; Herpesvirus 4, Human/pathogenicity; Humans; Prognosis; Thymidine Kinase/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Arginine / Thymidine Kinase / Lymphoma, Non-Hodgkin / Butyrates / Ganciclovir / Gene Expression Regulation, Neoplastic / Herpesvirus 4, Human / Epstein-Barr Virus Infections / Antineoplastic Agents Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Curr Opin Oncol Journal subject: NEOPLASIAS Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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