The selective mGlu(5) receptor agonist CHPG inhibits quinpirole-induced turning in 6-hydroxydopamine-lesioned rats and modulates the binding characteristics of dopamine D(2) receptors in the rat striatum: interactions with adenosine A(2a) receptors.

Popoli, P; Pèzzola, A; Torvinen, M; Reggio, R; Pintor, A; Scarchilli, L; Fuxe, K; Ferré, S

Popoli, P; Pèzzola, A; Torvinen, M; Reggio, R; Pintor, A; Scarchilli, L; Fuxe, K; Ferré, S.

Affiliation

Popoli P; Department of Pharmacology, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy. patrizia.popoli@iss.it

Neuropsychopharmacology ; 25(4): 505-13, 2001 Oct.

Article in En | MEDLINE | ID: mdl-11557164

Subject(s)

Dopamine Agonists/pharmacology; Excitatory Amino Acid Agonists/pharmacology; Glycine/pharmacology; Neostriatum/metabolism; Phenylacetates/pharmacology; Quinpirole/antagonists & inhibitors; Receptors, Dopamine D2/metabolism; Receptors, Metabotropic Glutamate/agonists; Receptors, Purinergic P1/metabolism; Stereotyped Behavior/drug effects; Sympathectomy, Chemical; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/pharmacology; Animals; Dopamine/metabolism; Excitatory Amino Acid Agonists/administration & dosage; Extracellular Space/metabolism; Functional Laterality; Glycine/administration & dosage; Glycine/analogs & derivatives; Injections, Intraventricular; Male; Microdialysis; Motor Activity/drug effects; Neostriatum/drug effects; Oxidopamine; Phenylacetates/administration & dosage; Quinpirole/pharmacology; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, Dopamine D1/agonists; Receptors, Dopamine D2/drug effects; Receptors, Purinergic P1/drug effects

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Phenylacetates / Stereotyped Behavior / Sympathectomy, Chemical / Receptors, Dopamine D2 / Neostriatum / Receptors, Purinergic P1 / Receptors, Metabotropic Glutamate / Excitatory Amino Acid Agonists / Dopamine Agonists / Quinpirole Limits: Animals Language: En Journal: Neuropsychopharmacology Journal subject: NEUROLOGIA / PSICOFARMACOLOGIA Year: 2001 Document type: Article Affiliation country: Italy

Search on Google

Add to My VHL

XML

PubMed Links