Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration.

Kluk, M J; Hla, T

Kluk, M J; Hla, T.

Affiliation

Kluk MJ; Center for Vascular Biology, Department of Physiology, University of Connecticut Health Center, Farmington, Connecticut, USA.

Circ Res ; 89(6): 496-502, 2001 Sep 14.

Article in En | MEDLINE | ID: mdl-11557736

Subject(s)

Immediate-Early Proteins/physiology; Lysophospholipids; Muscle, Smooth, Vascular/cytology; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Animals; Animals, Newborn; Cell Division/drug effects; Cell Movement/drug effects; Cells, Cultured; Culture Media, Serum-Free/pharmacology; Cyclin D1/drug effects; Cyclin D1/metabolism; DNA/biosynthesis; DNA/drug effects; Dose-Response Relationship, Drug; Enzyme Activation/drug effects; Gene Expression Regulation/drug effects; Immediate-Early Proteins/genetics; Muscle, Smooth, Vascular/drug effects; Muscle, Smooth, Vascular/metabolism; Pertussis Toxin; Protein Isoforms/genetics; RNA, Messenger/drug effects; RNA, Messenger/genetics; RNA, Messenger/metabolism; Rats; Rats, Wistar; Receptors, Lysophospholipid; Ribosomal Protein S6 Kinases/drug effects; Ribosomal Protein S6 Kinases/metabolism; Sirolimus/pharmacology; Sphingosine/analogs & derivatives; Sphingosine/pharmacology; Transfection; Virulence Factors, Bordetella/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Lysophospholipids / Immediate-Early Proteins / Receptors, Cell Surface / Receptors, G-Protein-Coupled / Muscle, Smooth, Vascular Language: En Journal: Circ Res Year: 2001 Document type: Article Affiliation country: United States

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