Neurotensin induces mating in Saccharomyces cerevisiae cells that express human neurotensin receptor type 1 in place of the endogenous pheromone receptor.

Leplatois, P; Josse, A; Guillemot, M; Febvre, M; Vita, N; Ferrara, P; Loison, G

Leplatois, P; Josse, A; Guillemot, M; Febvre, M; Vita, N; Ferrara, P; Loison, G.

Affiliation

Leplatois P; Molecular and Functional Genomics Department, Sanofi-Synthelabo Recherche, Labège, France.

Eur J Biochem ; 268(18): 4860-7, 2001 Sep.

Article in En | MEDLINE | ID: mdl-11559354

Subject(s)

Diploidy; Gene Deletion; Neurotensin/pharmacology; Receptors, Neurotensin/metabolism; Receptors, Peptide/genetics; Saccharomyces cerevisiae/cytology; Saccharomyces cerevisiae/drug effects; Transcription Factors; Binding, Competitive; Blotting, Western; Gene Expression Regulation, Fungal/drug effects; Genes, Reporter/genetics; Heterotrimeric GTP-Binding Proteins/chemistry; Heterotrimeric GTP-Binding Proteins/metabolism; Humans; Mating Factor; Neurotensin/antagonists & inhibitors; Neurotensin/metabolism; Peptides/pharmacology; Pheromones/pharmacology; Protein Subunits; Pyrazoles/pharmacology; Quinolines/pharmacology; Receptors, Mating Factor; Receptors, Neurotensin/antagonists & inhibitors; Receptors, Neurotensin/genetics; Receptors, Peptide/metabolism; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism; Signal Transduction/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Saccharomyces cerevisiae / Transcription Factors / Neurotensin / Gene Deletion / Receptors, Peptide / Receptors, Neurotensin / Diploidy Limits: Humans Language: En Journal: Eur J Biochem Year: 2001 Document type: Article Affiliation country: France Country of publication: United kingdom

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