Genome-wide scan for Parkinson's disease: the GenePD Study.
Neurology
; 57(6): 1124-6, 2001 Sep 25.
Article
in En
| MEDLINE
| ID: mdl-11571351
A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214 cM, lod = 1.20), 9 (136 cM, lod = 1.30), 10 (88 cM, lod = 1.07), and 16 (114 cM, lod = 0.93). The chromosome 9 region overlaps the genes for dopamine beta-hydroxylase and torsion dystonia. Although no strong evidence for linkage was found for any locus, these results may be of value in comparison with similar studies by others.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parkinson Disease
/
Genetic Testing
/
Genome
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Aged
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Neurology
Year:
2001
Document type:
Article
Affiliation country:
United States
Country of publication:
United States