Nitric oxide suppresses the expression of Bcl-2 binding protein BNIP3 in hepatocytes.

Zamora, R; Alarcon, L; Vodovotz, Y; Betten, B; Kim, P K; Gibson, K F; Billiar, T R

Zamora, R; Alarcon, L; Vodovotz, Y; Betten, B; Kim, P K; Gibson, K F; Billiar, T R.

Affiliation

Zamora R; Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15261, USA. zamorar@pitt.edu

J Biol Chem ; 276(50): 46887-95, 2001 Dec 14.

Article in En | MEDLINE | ID: mdl-11592958

Subject(s)

Gene Expression Regulation; Hepatocytes/metabolism; Liver/metabolism; Membrane Proteins/biosynthesis; Nitric Oxide/metabolism; Proto-Oncogene Proteins c-bcl-2/metabolism; Proto-Oncogene Proteins; Tumor Suppressor Proteins; Adenoviridae/genetics; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Cell Survival; Cells, Cultured; DNA, Complementary/metabolism; Dactinomycin/pharmacology; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors/pharmacology; Gene Expression Profiling; Gene Transfer Techniques; Guanylate Cyclase/antagonists & inhibitors; Guanylate Cyclase/metabolism; Humans; Male; Mice; Mice, Knockout; Nitric Oxide Donors/pharmacology; Nitric Oxide Synthase/metabolism; Nitric Oxide Synthase Type II; Nitrites/metabolism; Perfusion; Protein Binding; RNA/metabolism; RNA, Messenger/metabolism; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine/pharmacology; Signal Transduction; Sodium Nitrite/pharmacology; Time Factors; Up-Regulation

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Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Proto-Oncogene Proteins / Proto-Oncogene Proteins c-bcl-2 / Hepatocytes / Tumor Suppressor Proteins / Liver / Membrane Proteins / Nitric Oxide Type of study: Prognostic_studies Language: En Journal: J Biol Chem Year: 2001 Document type: Article Affiliation country: United States

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