Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.

Zhu, X; Castellani, R J; Takeda, A; Nunomura, A; Atwood, C S; Perry, G; Smith, M A

Zhu, X; Castellani, R J; Takeda, A; Nunomura, A; Atwood, C S; Perry, G; Smith, M A.

Affiliation

Zhu X; Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106, USA.

Mech Ageing Dev ; 123(1): 39-46, 2001 Dec.

Article in En | MEDLINE | ID: mdl-11640950

Subject(s)

Alzheimer Disease/enzymology; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinases/metabolism; Neurons/enzymology; Adolescent; Adult; Aged; Aged, 80 and over; Alzheimer Disease/pathology; Cerebral Cortex/enzymology; Cerebral Cortex/pathology; Enzyme Activation; Hippocampus/enzymology; Hippocampus/pathology; Humans; JNK Mitogen-Activated Protein Kinases; Middle Aged; Mitogen-Activated Protein Kinase 3; Phosphorylation; p38 Mitogen-Activated Protein Kinases

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Collection: 01-internacional Database: MEDLINE Main subject: Mitogen-Activated Protein Kinase 1 / Mitogen-Activated Protein Kinases / Alzheimer Disease / Neurons Limits: Adolescent / Adult / Aged / Aged80 / Humans / Middle aged Language: En Journal: Mech Ageing Dev Year: 2001 Document type: Article Affiliation country: United States

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