Fish oil supplementation improves visual evoked potentials in children with phenylketonuria.
Neurology
; 57(8): 1488-91, 2001 Oct 23.
Article
in En
| MEDLINE
| ID: mdl-11673596
ABSTRACT
Visual evoked potentials (VEP) were measured in 36 patients with early-treated phenylketonuria (PKU; aged 1 to 11 years) and good metabolic control before and after supplementation with omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) from fish oil. Patients with PKU had significantly longer P100 latencies than 22 age-matched control subjects. After 3 months of LC-PUFA supplementation, VEP latencies improved significantly in PKU patients but did not change in 12 untreated healthy children. The authors conclude that omega-3 LC-PUFA are essential substrates for nervous system function even beyond infancy.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phenylketonurias
/
Fish Oils
/
Evoked Potentials, Visual
Type of study:
Clinical_trials
Limits:
Child
/
Child, preschool
/
Humans
/
Infant
Language:
En
Journal:
Neurology
Year:
2001
Document type:
Article
Affiliation country:
Germany