Characterisation, cloning and sequencing of a conformation-dependent monoclonal antibody to the alphaIIbbeta3 integrin: interest for use in thrombus detection.

Dabadie, M; Valli, N; Jacobin, M J; Laroche-Traineau, J; Barat, J L; Ducassou, D; Nurden, A T; Clofent-Sanchez, G

Dabadie, M; Valli, N; Jacobin, M J; Laroche-Traineau, J; Barat, J L; Ducassou, D; Nurden, A T; Clofent-Sanchez, G.

Affiliation

Dabadie M; Equipe Imagerie Médical EA 1699, Laboratoire de Biophysique, Université de Bordeaux II, 146 Rue Léo-Saignat, 33076 Bordeaux, France. michele.dabadie@u-bordeaux2.fr

Platelets ; 12(7): 395-405, 2001 Nov.

Article in En | MEDLINE | ID: mdl-11674856

Subject(s)

Antibodies, Monoclonal/chemistry; Antibodies, Monoclonal/pharmacokinetics; Immunoconjugates/pharmacokinetics; Platelet Glycoprotein GPIIb-IIIa Complex/immunology; Amino Acid Motifs; Amino Acid Sequence; Animals; Antibody Affinity/drug effects; Antibody Specificity; Binding Sites/immunology; Cloning, Molecular; Disease Models, Animal; Edetic Acid/pharmacology; Immunoconjugates/chemistry; Iodine Radioisotopes; Male; Molecular Sequence Data; Platelet Activation/drug effects; Protein Conformation; Rabbits; Radionuclide Imaging; Sequence Analysis; Thrombin/pharmacology; Thrombosis/diagnostic imaging

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Collection: 01-internacional Database: MEDLINE Main subject: Immunoconjugates / Platelet Glycoprotein GPIIb-IIIa Complex / Antibodies, Monoclonal Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Platelets Journal subject: HEMATOLOGIA Year: 2001 Document type: Article Affiliation country: France Country of publication: United kingdom

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