Signals delivered through TCR instruct IL-12 receptor (IL-12R) expression: IL-12 and tumor necrosis factor-alpha synergize for IL-12R expression at low antigen dose.

Ahlers, J D; Belyakov, I M; Matsui, S; Berzofsky, J A

Ahlers, J D; Belyakov, I M; Matsui, S; Berzofsky, J A.

Affiliation

Ahlers JD; Molecular Immunogenetics and Vaccine Research Section, Metabolism Branch, National Cancer Institute, National Institute of Health, Bethesda, MD 20892, USA.

Int Immunol ; 13(11): 1433-42, 2001 Nov.

Article in En | MEDLINE | ID: mdl-11675375

Subject(s)

Interleukin-12/pharmacology; Receptors, Interleukin/metabolism; T-Lymphocytes/immunology; Tumor Necrosis Factor-alpha/pharmacology; Animals; Cell Differentiation/drug effects; Female; Interferon-gamma/biosynthesis; Interleukin-12/physiology; Mice; Mice, Inbred BALB C; Receptors, Interleukin-12; Signal Transduction; Th1 Cells/immunology; Tumor Necrosis Factor-alpha/physiology; Up-Regulation

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Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Tumor Necrosis Factor-alpha / Receptors, Interleukin / Interleukin-12 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Int Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2001 Document type: Article Affiliation country: United States

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