Characterization of the signal transduction pathways mediating morphine withdrawal-stimulated c-fos expression in hypothalamic nuclei.

Martínez, P J; Laorden, M L; Cerezo, M; Martínez-Piñero, M G; Milanés, M V

Martínez, P J; Laorden, M L; Cerezo, M; Martínez-Piñero, M G; Milanés, M V.

Affiliation

Martínez PJ; Department of Pharmacology, Faculty of Medicine, Campus de Espinardo, 30100, Murcia, Spain.

Eur J Pharmacol ; 430(1): 59-68, 2001 Oct 26.

Article in En | MEDLINE | ID: mdl-11698063

Subject(s)

Anterior Hypothalamic Nucleus/drug effects; Morphine/adverse effects; Proto-Oncogene Proteins c-fos/biosynthesis; Signal Transduction/physiology; Animals; Anterior Hypothalamic Nucleus/metabolism; Calcium/metabolism; Calcium Channels, L-Type/drug effects; Cyclic AMP-Dependent Protein Kinases/antagonists & inhibitors; Hypothalamo-Hypophyseal System/drug effects; Male; Naloxone/administration & dosage; Paraventricular Hypothalamic Nucleus/drug effects; Paraventricular Hypothalamic Nucleus/metabolism; Pituitary-Adrenal System/drug effects; Protein Kinase C/antagonists & inhibitors; Proto-Oncogene Proteins c-fos/analysis; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome/metabolism; Supraoptic Nucleus/drug effects; Supraoptic Nucleus/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Proto-Oncogene Proteins c-fos / Anterior Hypothalamic Nucleus / Morphine Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2001 Document type: Article Affiliation country: Spain

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