Inhibition of placental 11beta-hydroxysteroid dehydrogenase type 2 by catecholamines via alpha-adrenergic signaling.

Sarkar, S; Tsai, S W; Nguyen, T T; Plevyak, M; Padbury, J F; Rubin, L P

Sarkar, S; Tsai, S W; Nguyen, T T; Plevyak, M; Padbury, J F; Rubin, L P.

Affiliation

Sarkar S; Department of Pediatrics, Brown Medical School, Providence, Rhode Island 02905-2499, USA.

Am J Physiol Regul Integr Comp Physiol ; 281(6): R1966-74, 2001 Dec.

Article in En | MEDLINE | ID: mdl-11705783

Subject(s)

Adrenergic alpha-Antagonists/pharmacology; Azepines/pharmacology; Hydroxysteroid Dehydrogenases/genetics; Placenta/enzymology; Receptors, Adrenergic, alpha/physiology; Trophoblasts/enzymology; Cell Line; Cells, Cultured; Cesarean Section; Chorionic Villi/enzymology; DNA Primers; Female; Gene Expression Regulation, Enzymologic/drug effects; Gestational Age; Humans; Hydroxysteroid Dehydrogenases/antagonists & inhibitors; Norepinephrine/pharmacology; Polymerase Chain Reaction; Pregnancy; Pregnancy Trimester, First; Propanolamines/pharmacology; Recombinant Proteins/genetics; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription, Genetic

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Collection: 01-internacional Database: MEDLINE Main subject: Placenta / Azepines / Trophoblasts / Receptors, Adrenergic, alpha / Adrenergic alpha-Antagonists / Hydroxysteroid Dehydrogenases Limits: Female / Humans / Pregnancy Language: En Journal: Am J Physiol Regul Integr Comp Physiol Journal subject: FISIOLOGIA Year: 2001 Document type: Article Affiliation country: United States Country of publication: United States

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