Clarithromycin resistance, but not CYP2C-19 polymorphism, has a major impact on treatment success in 7-day treatment regimen for cure of H. pylori infection: a multiple logistic regression analysis.

Miwa, H; Misawa, H; Yamada, T; Nagahara, A; Ohtaka, K; Sato, N

Miwa, H; Misawa, H; Yamada, T; Nagahara, A; Ohtaka, K; Sato, N.

Affiliation

Miwa H; Department of Gastroenterology, Juntendo University, School of Medicine, Tokyo, Japan.

Dig Dis Sci ; 46(11): 2445-50, 2001 Nov.

Article in En | MEDLINE | ID: mdl-11713950

Subject(s)

Aryl Hydrocarbon Hydroxylases; Clarithromycin/pharmacology; Cytochrome P-450 Enzyme System/genetics; Helicobacter Infections/drug therapy; Helicobacter pylori; Mixed Function Oxygenases/genetics; Amoxicillin/therapeutic use; Anti-Bacterial Agents/therapeutic use; Clarithromycin/therapeutic use; Cytochrome P-450 CYP2C19; Drug Resistance, Bacterial; Drug Therapy, Combination; Dyspepsia/microbiology; Female; Helicobacter pylori/drug effects; Humans; Logistic Models; Male; Middle Aged; Omeprazole/therapeutic use; Penicillins/therapeutic use; Peptic Ulcer/microbiology; Polymorphism, Genetic; Prospective Studies; Proton Pump Inhibitors; Time Factors; Treatment Outcome

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Collection: 01-internacional Database: MEDLINE Main subject: Aryl Hydrocarbon Hydroxylases / Helicobacter pylori / Helicobacter Infections / Clarithromycin / Cytochrome P-450 Enzyme System / Mixed Function Oxygenases Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Dig Dis Sci Year: 2001 Document type: Article Affiliation country: Japan

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