A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival.

Rattner, A; Smallwood, P M; Williams, J; Cooke, C; Savchenko, A; Lyubarsky, A; Pugh, E N; Nathans, J

Rattner, A; Smallwood, P M; Williams, J; Cooke, C; Savchenko, A; Lyubarsky, A; Pugh, E N; Nathans, J.

Affiliation

Rattner A; Department of Molecular Biology and Genetics, Baltimore, MD 21205, USA.

Neuron ; 32(5): 775-86, 2001 Dec 06.

Article in En | MEDLINE | ID: mdl-11738025

Subject(s)

Cadherins/chemistry; Cadherins/physiology; Photoreceptor Cells/chemistry; Photoreceptor Cells/physiology; Rod Cell Outer Segment/physiology; Amino Acid Sequence; Animals; Cadherins/genetics; Cadherins/metabolism; Cattle; Cell Death/physiology; Cell Survival/genetics; Chick Embryo; Genotype; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Organ Specificity/genetics; Photoreceptor Cells/metabolism; Photoreceptor Cells/ultrastructure; Rabbits; Rats; Retina/chemistry; Retina/metabolism; Retina/ultrastructure; Rod Cell Outer Segment/chemistry; Rod Cell Outer Segment/ultrastructure; Structure-Activity Relationship; Subcellular Fractions/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Photoreceptor Cells / Rod Cell Outer Segment / Cadherins Limits: Animals / Humans Language: En Journal: Neuron Journal subject: NEUROLOGIA Year: 2001 Document type: Article Affiliation country: United States

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