Human myofibroblastic hepatic stellate cells express Ca(2+)-activated K(+) channels that modulate the effects of endothelin-1 and nitric oxide.

Gasull, X; Bataller, R; Ginès, P; Sancho-Bru, P; Nicolás, J M; Görbig, M N; Ferrer, E; Badía, E; Gual, A; Arroyo, V; Rodés, J

Gasull, X; Bataller, R; Ginès, P; Sancho-Bru, P; Nicolás, J M; Görbig, M N; Ferrer, E; Badía, E; Gual, A; Arroyo, V; Rodés, J.

Affiliation

Gasull X; Laboratory of Neurophysiology, University of Barcelona School of Medicine, IDIBAPS, Catalonia, Barcelona, Spain.

J Hepatol ; 35(6): 739-48, 2001 Dec.

Article in En | MEDLINE | ID: mdl-11738101

Subject(s)

Endothelin-1/pharmacology; Fibroblasts/metabolism; Liver/metabolism; Muscle, Smooth/metabolism; Nitric Oxide/physiology; Potassium Channels, Calcium-Activated/physiology; Benzimidazoles/pharmacology; Calcium/metabolism; Cells, Cultured; Fibroblasts/physiology; Humans; Large-Conductance Calcium-Activated Potassium Channels; Liver/cytology; Muscle, Smooth/cytology; Muscle, Smooth/physiology; Nitric Oxide Donors/pharmacology; Patch-Clamp Techniques; Peptides/pharmacology; Potassium Channels, Calcium-Activated/agonists; Potassium Channels, Calcium-Activated/antagonists & inhibitors; S-Nitroso-N-Acetylpenicillamine/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Endothelin-1 / Potassium Channels, Calcium-Activated / Fibroblasts / Liver / Muscle, Smooth / Nitric Oxide Limits: Humans Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2001 Document type: Article Affiliation country: Spain Country of publication: Netherlands

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