Endotoxin induces desensitization of cardiac endothelin-1 receptor signaling by increased expression of RGS4 and RGS16.

Patten, Monica; Bünemann, Jan; Thoma, Bryan; Krämer, Elisabeth; Thoenes, Martin; Stübe, Sabine; Mittmann, Clemens; Wieland, Thomas

Patten, Monica; Bünemann, Jan; Thoma, Bryan; Krämer, Elisabeth; Thoenes, Martin; Stübe, Sabine; Mittmann, Clemens; Wieland, Thomas.

Affiliation

Patten M; Medizinische Klinik, Abteilung für Kardiologie, Universitäts-Krankenhaus Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, FRG. patten@uke.uni-hamburg.de

Cardiovasc Res ; 53(1): 156-64, 2002 Jan.

Article in En | MEDLINE | ID: mdl-11744024

Subject(s)

Heart Failure/metabolism; Lipopolysaccharides/pharmacology; Myocardium/metabolism; RGS Proteins/metabolism; Receptors, Endothelin/metabolism; Signal Transduction/drug effects; Animals; Blotting, Western; Cells, Cultured; GTP-Binding Proteins/metabolism; Male; Proteins/genetics; Proteins/metabolism; RGS Proteins/genetics; RNA, Messenger/analysis; Rats; Rats, Wistar; Type C Phospholipases/analysis; Type C Phospholipases/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Lipopolysaccharides / Receptors, Endothelin / RGS Proteins / Heart Failure / Myocardium Limits: Animals Language: En Journal: Cardiovasc Res Year: 2002 Document type: Article Country of publication: United kingdom

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