Human angiogenin fused to human CD30 ligand (Ang-CD30L) exhibits specific cytotoxicity against CD30-positive lymphoma.

Huhn, M; Sasse, S; Tur, M K; Matthey, B; Schinköthe, T; Rybak, S M; Barth, S; Engert, A

Huhn, M; Sasse, S; Tur, M K; Matthey, B; Schinköthe, T; Rybak, S M; Barth, S; Engert, A.

Affiliation

Huhn M; Fraunhofer IME, Department of Pharmaceutical Product Development, 52074 Aachen, Germany.

Cancer Res ; 61(24): 8737-42, 2001 Dec 15.

Article in En | MEDLINE | ID: mdl-11751393

Subject(s)

Hodgkin Disease/drug therapy; Immunotoxins/pharmacology; Ki-1 Antigen/metabolism; Membrane Glycoproteins/pharmacology; Recombinant Fusion Proteins/pharmacology; Ribonuclease, Pancreatic/pharmacology; CD30 Ligand; Cloning, Molecular; Hodgkin Disease/immunology; Hodgkin Disease/metabolism; Humans; Immunotoxins/genetics; Immunotoxins/metabolism; Ki-1 Antigen/immunology; Membrane Glycoproteins/genetics; Membrane Glycoproteins/metabolism; Plasmids/genetics; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/metabolism; Ribonuclease, Pancreatic/genetics; Ribonuclease, Pancreatic/metabolism; Ribonucleases/metabolism; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Ribonuclease, Pancreatic / Recombinant Fusion Proteins / Hodgkin Disease / Membrane Glycoproteins / Immunotoxins / Ki-1 Antigen Limits: Humans Language: En Journal: Cancer Res Year: 2001 Document type: Article Affiliation country: Germany Country of publication: United States

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