The effects of deleting the mouse neurotensin receptor NTR1 on central and peripheral responses to neurotensin.

Pettibone, Douglas J; Hess, J Fred; Hey, Patricia J; Jacobson, Marlene A; Leviten, Michael; Lis, Edward V; Mallorga, Pierre J; Pascarella, Danette M; Snyder, Melissa A; Williams, Jacinta B; Zeng, Zhizhen

Pettibone, Douglas J; Hess, J Fred; Hey, Patricia J; Jacobson, Marlene A; Leviten, Michael; Lis, Edward V; Mallorga, Pierre J; Pascarella, Danette M; Snyder, Melissa A; Williams, Jacinta B; Zeng, Zhizhen.

Affiliation

Pettibone DJ; Department of Neuroscience, Merck Research Laboratories, West Point, Pennsylvania 19486, USA. doug_pettibone@merck.com

J Pharmacol Exp Ther ; 300(1): 305-13, 2002 Jan.

Article in En | MEDLINE | ID: mdl-11752130

Subject(s)

Central Nervous System/drug effects; Neurotensin/pharmacology; Peripheral Nervous System/drug effects; Receptors, Neurotensin/physiology; Analgesics/pharmacology; Animals; Blotting, Northern; Body Temperature/drug effects; Cell Line; Gastrointestinal Motility/drug effects; In Situ Hybridization; Mice; Mice, Inbred C57BL; Mice, Knockout; Pain Measurement/drug effects; Phenotype; Postural Balance/drug effects; Psychomotor Performance/drug effects; RNA, Messenger/biosynthesis; Radioligand Assay; Receptors, Neurotensin/genetics; Reverse Transcriptase Polymerase Chain Reaction

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Collection: 01-internacional Database: MEDLINE Main subject: Neurotensin / Central Nervous System / Receptors, Neurotensin / Peripheral Nervous System Limits: Animals Language: En Journal: J Pharmacol Exp Ther Year: 2002 Document type: Article Affiliation country: United States Country of publication: United States

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