Polymer-supported approach for solution-phase synthesis of cysteine trap protease inhibitors: procedure for straightforward optimization of the P1-P1' pocket.

Yadav-Bhatnagar, Neerja; Desjonquères, Nicolas; Mauger, Jacques

Yadav-Bhatnagar, Neerja; Desjonquères, Nicolas; Mauger, Jacques.

Affiliation

Yadav-Bhatnagar N; Automated Synthesis & New Technologies, Aventis Pharma, 102 Route de Noisy, F-93325 Romainville Cedex, France. neerja.bhatnagar@aventis.com

J Comb Chem ; 4(1): 49-55, 2002.

Article in En | MEDLINE | ID: mdl-11831882

Subject(s)

Combinatorial Chemistry Techniques/methods; Cysteine Proteinase Inhibitors/chemical synthesis; Binding Sites; Cysteine Proteinase Inhibitors/chemistry; Diazonium Compounds/chemical synthesis; Diazonium Compounds/chemistry; Drug Design; Molecular Mimicry; Molecular Probes/chemical synthesis; Molecular Probes/chemistry; Oligopeptides/chemical synthesis; Oligopeptides/chemistry; Polymers/chemistry

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Cysteine Proteinase Inhibitors / Combinatorial Chemistry Techniques Language: En Journal: J Comb Chem Journal subject: QUIMICA Year: 2002 Document type: Article Affiliation country: France Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links