An unusual case of anti-Borrelia burgdorferi immunoglobulin G seroconversion caused by administration of intravenous gammaglobulins.
Clin Microbiol Infect
; 7(12): 697-9, 2001 Dec.
Article
in En
| MEDLINE
| ID: mdl-11843914
ABSTRACT
Administration of gammaglobulins to individuals without specific anti-Borrelia burgdorferi antibodies may lead to immunoglobulin G (IgG) conversion as detected by enzyme-linked immunosorbent assay (ELISA). In some cases however, complementary techniques such as Western blot or avidity will be of prime importance in distinguishing the start of an infection from the passive immunization induced by the gammaglobulins. In all cases, the key element before reaching conclusions in relation to any of these investigations remains the confrontation between the clinical context and the biological findings. This is the scenario that has been followed in our observation.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Lyme Disease
/
Immunoglobulins, Intravenous
/
Borrelia burgdorferi
Type of study:
Diagnostic_studies
Limits:
Child, preschool
/
Humans
/
Male
Language:
En
Journal:
Clin Microbiol Infect
Journal subject:
DOENCAS TRANSMISSIVEIS
/
MICROBIOLOGIA
Year:
2001
Document type:
Article
Affiliation country:
Belgium