PLGA-mPEG nanoparticles of cisplatin: in vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in blood properties.

Avgoustakis, K; Beletsi, A; Panagi, Z; Klepetsanis, P; Karydas, A G; Ithakissios, D S

Avgoustakis, K; Beletsi, A; Panagi, Z; Klepetsanis, P; Karydas, A G; Ithakissios, D S.

Affiliation

Avgoustakis K; Pharmaceutical Technology Laboratory, Department of Pharmacy, University of Patras, 26500, Rion, Greece. avgoust@upatras.gr

J Control Release ; 79(1-3): 123-35, 2002 Feb 19.

Article in En | MEDLINE | ID: mdl-11853924

Subject(s)

Cisplatin/pharmacokinetics; Polyethylene Glycols/pharmacokinetics; Polyglactin 910/pharmacokinetics; Animals; Antineoplastic Agents/blood; Antineoplastic Agents/pharmacokinetics; Biocompatible Materials/pharmacokinetics; Cisplatin/blood; Delayed-Action Preparations/pharmacokinetics; Drug Carriers/pharmacokinetics; Drug Evaluation, Preclinical/methods; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Nanotechnology/methods; Particle Size

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Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Polyglactin 910 / Cisplatin Limits: Animals Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2002 Document type: Article Affiliation country: Greece Country of publication: Netherlands

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