Simultaneous determination of furanocoumarins in infusions and decoctions from "Carapiá" (dorstenia species) by high-performance liquid chromatography.
J Agric Food Chem
; 50(6): 1465-9, 2002 Mar 13.
Article
in En
| MEDLINE
| ID: mdl-11879022
ABSTRACT
The use of furanocoumarins, which are photosensitizing compounds, combined with exposure to UV-A radiation is a common treatment for vitiligo, psoriasis, and a number of other skin diseases. Although furanocoumarins plus UV-A treatment is highly effective, several studies have shown that exposure to high doses increases the risk to development of cutaneus carcinoma. Several Dorstenia species are used in folk medicine, mainly against skin diseases, because of the presence of biologically active compounds. We present here analysis of the chemical composition of furanocoumarins from infusion and decoction of "Carapiá" (Dorstenia species), which is used in Brazil against several diseases. We have employed high-performance liquid chromatography (HPLC) procedures for the quantitative determination of psoralen, bergapten, and isopimpinellin. The contents of furanocoumarins revealed an insignificant difference between infusion and decoction. Dorstenia tubicina and D. asaroides contained psoralen and bergapten only in the rhizomes, whereas D. vitifolia shows solely isopimpinellin in both rhizomes and aerial parts.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plants, Medicinal
/
Furocoumarins
/
Chromatography, High Pressure Liquid
/
Photosensitizing Agents
/
Methoxsalen
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
J Agric Food Chem
Year:
2002
Document type:
Article
Affiliation country:
Brazil