Leukotriene B4 receptor antagonism reduces monocytic foam cells in mice.

Aiello, Robert J; Bourassa, Patricia-Ann; Lindsey, Saralyn; Weng, Weifan; Freeman, Ann; Showell, Henry J

Aiello, Robert J; Bourassa, Patricia-Ann; Lindsey, Saralyn; Weng, Weifan; Freeman, Ann; Showell, Henry J.

Affiliation

Aiello RJ; Department of Cardiovascular and Metabolic Disease, Pfizer Global Research and Development, Groton, Conn 06340, USA. robert_j_aiello@groton.pfizer.com.

Arterioscler Thromb Vasc Biol ; 22(3): 443-9, 2002 Mar 01.

Article in En | MEDLINE | ID: mdl-11884288

Subject(s)

Arteriosclerosis/etiology; Benzopyrans/pharmacology; Carboxylic Acids/pharmacology; Foam Cells; Leukotriene Antagonists/pharmacology; Receptors, Leukotriene B4/antagonists & inhibitors; Animals; Apolipoproteins E/genetics; Arteriosclerosis/metabolism; Arteriosclerosis/pathology; Chemokine CCL2/genetics; Disease Progression; Immunohistochemistry; Leukotriene B4/physiology; Lipids/blood; Macrophage-1 Antigen/immunology; Macrophage-1 Antigen/metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes/cytology; Monocytes/metabolism; Receptors, CCR2; Receptors, Chemokine/metabolism; Receptors, LDL/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Arteriosclerosis / Benzopyrans / Carboxylic Acids / Receptors, Leukotriene B4 / Leukotriene Antagonists / Foam Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2002 Document type: Article Affiliation country: United States

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