Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae.

Razani, Babak; Wang, Xiao Bo; Engelman, Jeffery A; Battista, Michela; Lagaud, Guy; Zhang, Xiao Lan; Kneitz, Burkhard; Hou, Harry; Christ, George J; Edelmann, Winfried; Lisanti, Michael P

Razani, Babak; Wang, Xiao Bo; Engelman, Jeffery A; Battista, Michela; Lagaud, Guy; Zhang, Xiao Lan; Kneitz, Burkhard; Hou, Harry; Christ, George J; Edelmann, Winfried; Lisanti, Michael P.

Affiliation

Razani B; Department of Molecular Pharmacology, Institute for Smooth Muscle Biology, The Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

Mol Cell Biol ; 22(7): 2329-44, 2002 Apr.

Article in En | MEDLINE | ID: mdl-11884617

Subject(s)

Caveolae/metabolism; Caveolins/deficiency; Caveolins/metabolism; Lung/metabolism; Lung/physiopathology; Adipose Tissue/cytology; Adipose Tissue/metabolism; Adipose Tissue/ultrastructure; Animals; Aorta/drug effects; Aorta/physiology; Body Weight; Caveolae/chemistry; Caveolae/ultrastructure; Caveolin 1; Caveolin 2; Caveolins/genetics; Exercise Tolerance/genetics; Exercise Tolerance/physiology; Fasting/metabolism; Female; Lung/pathology; Lung/ultrastructure; Male; Mice; Mice, Knockout; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Nitric Oxide/pharmacology; Postprandial Period

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Caveolae / Caveolins / Lung Limits: Animals Language: En Journal: Mol Cell Biol Year: 2002 Document type: Article Affiliation country: United States Country of publication: United States

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