Renal toxicity of perchloroethylene and S-(1,2,2-trichlorovinyl)glutathione in rats and mice: sex- and species-dependent differences.

Lash, Lawrence H; Qian, Wei; Putt, David A; Hueni, Sarah E; Elfarra, Adnan A; Sicuri, Anna Rita; Parker, Jean C

Lash, Lawrence H; Qian, Wei; Putt, David A; Hueni, Sarah E; Elfarra, Adnan A; Sicuri, Anna Rita; Parker, Jean C.

Affiliation

Lash LH; Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA. l.h.lash@wayne.edu

Toxicol Appl Pharmacol ; 179(3): 163-71, 2002 Mar 15.

Article in En | MEDLINE | ID: mdl-11906246

Subject(s)

Environmental Pollutants/toxicity; Glutathione/analogs & derivatives; Glutathione/toxicity; Kidney Diseases/chemically induced; Tetrachloroethylene/toxicity; Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; Female; Kidney Diseases/pathology; L-Lactate Dehydrogenase/biosynthesis; Liver Diseases/pathology; Male; Mice; Mitochondria/drug effects; Mitochondria/metabolism; Rats; Rats, Inbred F344; Sex Characteristics; Species Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Tetrachloroethylene / Environmental Pollutants / Glutathione / Kidney Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2002 Document type: Article Affiliation country: United States Country of publication: United States

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