Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice.

Bao, Lihua; Haas, Mark; Boackle, Susan A; Kraus, Damian M; Cunningham, Patrick N; Park, Pierce; Alexander, Jessy J; Anderson, Randall K; Culhane, Kristin; Holers, V Michael; Quigg, Richard J

Bao, Lihua; Haas, Mark; Boackle, Susan A; Kraus, Damian M; Cunningham, Patrick N; Park, Pierce; Alexander, Jessy J; Anderson, Randall K; Culhane, Kristin; Holers, V Michael; Quigg, Richard J.

Affiliation

Bao L; Department of Medicine, Section of Nephrology, University of Chicago, Chicago, IL 60637, USA.

J Immunol ; 168(7): 3601-7, 2002 Apr 01.

Article in En | MEDLINE | ID: mdl-11907125

Subject(s)

Complement Inactivator Proteins/biosynthesis; Complement Inactivator Proteins/genetics; Lupus Nephritis/immunology; Lupus Nephritis/mortality; Receptors, Complement/biosynthesis; Receptors, Complement/genetics; Transgenes/immunology; Animals; Autoimmune Diseases/genetics; Autoimmune Diseases/immunology; Complement C3/metabolism; Complement Inactivator Proteins/physiology; Immunoglobulin G/metabolism; Kidney Glomerulus/metabolism; Kidney Glomerulus/pathology; Lupus Nephritis/pathology; Lupus Nephritis/prevention & control; Mice; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Mice, Transgenic; Receptors, Complement/physiology; Receptors, Complement 3b; Survival Analysis

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Lupus Nephritis / Complement Inactivator Proteins / Receptors, Complement / Transgenes Limits: Animals Language: En Journal: J Immunol Year: 2002 Document type: Article Affiliation country: United States

Search on Google

Add to My VHL

XML

PubMed Links