Nickel essentiality, toxicity, and carcinogenicity.
Crit Rev Oncol Hematol
; 42(1): 35-56, 2002 Apr.
Article
in En
| MEDLINE
| ID: mdl-11923067
ABSTRACT
The increasing utilization of heavy metals in modern industries leads to an increase in the environmental burden. Nickel represents a good example of a metal whose use is widening in modern technologies. As the result of accelerated consumption of nickel-containing products nickel compounds are released to the environment at all stages of production and utilization. Their accumulation in the environment may represent a serious hazard to human health. Among the known health related effects of nickel are skin allergies, lung fibrosis, variable degrees of kidney and cardiovascular system poisoning and stimulation of neoplastic transformation. The mechanism of the latter effect is not known and is the subject of detailed investigation. This review provides an analysis of the current state in the field.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Nickel
Limits:
Animals
/
Female
/
Humans
/
Male
Language:
En
Journal:
Crit Rev Oncol Hematol
Journal subject:
HEMATOLOGIA
/
NEOPLASIAS
Year:
2002
Document type:
Article
Affiliation country:
Germany