B7-CTLA4 interaction promotes cognate destruction of tumor cells by cytotoxic T lymphocytes in vivo.

Bai, Xue-Feng; Liu, Jinqing; May, Kenneth F; Guo, Yong; Zheng, Pan; Liu, Yang

Bai, Xue-Feng; Liu, Jinqing; May, Kenneth F; Guo, Yong; Zheng, Pan; Liu, Yang.

Affiliation

Bai XF; Department of Pathology and the Comprehensive Cancer Center, Ohio State University Medical Center, Columbus 43210, USA.

Blood ; 99(8): 2880-9, 2002 Apr 15.

Article in En | MEDLINE | ID: mdl-11929778

Subject(s)

Antigens, Differentiation/metabolism; Antigens, Neoplasm/immunology; B7-1 Antigen/metabolism; Immunoconjugates; T-Lymphocytes, Cytotoxic/immunology; Abatacept; Adoptive Transfer; Animals; Antigens, CD/genetics; Antigens, CD/immunology; Antigens, CD/metabolism; Antigens, Differentiation/immunology; B7-1 Antigen/genetics; B7-1 Antigen/immunology; B7-2 Antigen; CD28 Antigens/genetics; CD28 Antigens/metabolism; CTLA-4 Antigen; Cytotoxicity, Immunologic/drug effects; Immunity; Lymphocyte Activation/drug effects; Membrane Glycoproteins/genetics; Membrane Glycoproteins/immunology; Membrane Glycoproteins/metabolism; Mice; Mice, Transgenic; Mutation; Neoplasms, Experimental/therapy; Protein Binding/immunology; Receptors, Antigen, T-Cell/immunology; T-Lymphocytes, Cytotoxic/transplantation

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Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Cytotoxic / Antigens, Differentiation / B7-1 Antigen / Immunoconjugates / Antigens, Neoplasm Limits: Animals Language: En Journal: Blood Year: 2002 Document type: Article Affiliation country: United States Country of publication: United States

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