A single split-signal FISH probe set allows detection of TAL1 translocations as well as SIL-TAL1 fusion genes in a single test.

van der Burg, M; Smit, B; Brinkhof, B; Barendregt, B H; Verschuren, M C M; Dib, M; Beverloo, H B; van Dongen, J J M; Langerak, A W

van der Burg, M; Smit, B; Brinkhof, B; Barendregt, B H; Verschuren, M C M; Dib, M; Beverloo, H B; van Dongen, J J M; Langerak, A W.

Affiliation

van der Burg M; Dept of Immunology, Erasmus University Rotterdam/University Hospital Rotterdam, The Netherlands.

Leukemia ; 16(4): 755-61, 2002 Apr.

Article in En | MEDLINE | ID: mdl-11960364

Subject(s)

Bacterial Proteins/genetics; DNA-Binding Proteins/genetics; Leukemia-Lymphoma, Adult T-Cell/genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics; Proto-Oncogene Proteins; Translocation, Genetic; Basic Helix-Loop-Helix Transcription Factors; Chromosome Breakage; Chromosomes, Human, Pair 1/genetics; Gene Deletion; Gene Library; Helix-Loop-Helix Motifs; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Leukemia-Lymphoma, Adult T-Cell/immunology; Oncogene Proteins, Fusion/genetics; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; T-Cell Acute Lymphocytic Leukemia Protein 1; Transcription Factors/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Translocation, Genetic / Leukemia-Lymphoma, Adult T-Cell / Proto-Oncogene Proteins / DNA-Binding Proteins / Precursor Cell Lymphoblastic Leukemia-Lymphoma Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2002 Document type: Article Affiliation country: Netherlands

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