TAp63gamma (p51A) and dNp63alpha (p73L), two major isoforms of the p63 gene, exert opposite effects on the vascular endothelial growth factor (VEGF) gene expression.

Senoo, Makoto; Matsumura, Yasuko; Habu, Sonoko

Senoo, Makoto; Matsumura, Yasuko; Habu, Sonoko.

Affiliation

Senoo M; Department of Immunology, Tokai University School of Medicine, Bouseidai, Isehara-city, Kanagawa 259-1193, Japan.

Oncogene ; 21(16): 2455-65, 2002 Apr 11.

Article in En | MEDLINE | ID: mdl-11971180

Subject(s)

DNA-Binding Proteins/physiology; Endothelial Growth Factors/genetics; Lymphokines/genetics; Membrane Proteins; Nuclear Proteins/physiology; Phosphoproteins/physiology; Trans-Activators/physiology; Animals; COS Cells; Cells, Cultured; DNA-Binding Proteins/genetics; Endothelial Growth Factors/biosynthesis; Gene Silencing; Genes, Tumor Suppressor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lymphokines/biosynthesis; Mice; Nuclear Proteins/genetics; Phosphoproteins/genetics; Promoter Regions, Genetic; Protein Isoforms/genetics; Protein Isoforms/physiology; RNA, Messenger/biosynthesis; Response Elements; Trans-Activators/genetics; Transcription Factors/metabolism; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Protein p53/metabolism; Tumor Suppressor Proteins; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Nuclear Proteins / Trans-Activators / Endothelial Growth Factors / Lymphokines / DNA-Binding Proteins / Membrane Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2002 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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