The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10.

DiMartino, Jorge F; Ayton, Paul M; Chen, Everett H; Naftzger, Clarissa C; Young, Bryan D; Cleary, Michael L

DiMartino, Jorge F; Ayton, Paul M; Chen, Everett H; Naftzger, Clarissa C; Young, Bryan D; Cleary, Michael L.

Affiliation

DiMartino JF; Department of Pathology, Stanford University School of Medicine, CA 94305, USA.

Blood ; 99(10): 3780-5, 2002 May 15.

Article in En | MEDLINE | ID: mdl-11986236

Subject(s)

Cell Transformation, Neoplastic; Leukemia, Myeloid/etiology; Myeloid Progenitor Cells/metabolism; Oncogene Proteins, Fusion/physiology; Proto-Oncogenes; Transcription Factors/genetics; Amino Acid Motifs; Amino Acid Sequence; Animals; COS Cells; Cell Line; Cells, Cultured; Conserved Sequence; DNA-Binding Proteins/genetics; Histone-Lysine N-Methyltransferase; Leucine Zippers; Leukemia, Myeloid/pathology; Mice; Mice, Inbred C57BL; Mice, SCID; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion/chemistry; Oncogene Proteins, Fusion/genetics; Protein Structure, Tertiary; Sequence Alignment; Transcription Factors/chemistry; Transcriptional Activation; Transduction, Genetic

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Proto-Oncogenes / Leukemia, Myeloid / Oncogene Proteins, Fusion / Cell Transformation, Neoplastic / Myeloid Progenitor Cells Limits: Animals Language: En Journal: Blood Year: 2002 Document type: Article Affiliation country: United States Country of publication: United States

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