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SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repair.
Ferzaz, Badia; Brault, Emmanuel; Bourliaud, Genevieve; Robert, Jean-Pierre; Poughon, Gilles; Claustre, Yves; Marguet, Franck; Liere, Philippe; Schumacher, Michael; Nowicki, Jean-Pierre; Fournier, Jacqueline; Marabout, Benoit; Sevrin, Mireille; George, Pascal; Soubrie, Philippe; Benavides, Jesus; Scatton, Bernard.
Affiliation
  • Ferzaz B; Discovery Research, Central Nervous System Research Department, Sanofi-Synthélabo Recherche, 31 avenue P. Vaillant-Couturier, 92225 Bagneux Cedex, France. badia.ferzaz@sanofi-synthelabo.com
J Pharmacol Exp Ther ; 301(3): 1067-78, 2002 Jun.
Article in En | MEDLINE | ID: mdl-12023539
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Collection: 01-internacional Database: MEDLINE Main subject: Neuroprotective Agents / GABA-A Receptor Agonists / Indoles / Acetamides / Motor Neurons Limits: Animals / Humans / Male Language: En Journal: J Pharmacol Exp Ther Year: 2002 Document type: Article Affiliation country: France Country of publication: United States
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Collection: 01-internacional Database: MEDLINE Main subject: Neuroprotective Agents / GABA-A Receptor Agonists / Indoles / Acetamides / Motor Neurons Limits: Animals / Humans / Male Language: En Journal: J Pharmacol Exp Ther Year: 2002 Document type: Article Affiliation country: France Country of publication: United States