15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure.

Leonard, Martin O; Hannan, Kieran; Burne, Melissa J; Lappin, David W P; Doran, Peter; Coleman, Patrick; Stenson, Catherine; Taylor, Cormac T; Daniels, Frank; Godson, Catherine; Petasis, Nicos A; Rabb, Hamid; Brady, Hugh R

Leonard, Martin O; Hannan, Kieran; Burne, Melissa J; Lappin, David W P; Doran, Peter; Coleman, Patrick; Stenson, Catherine; Taylor, Cormac T; Daniels, Frank; Godson, Catherine; Petasis, Nicos A; Rabb, Hamid; Brady, Hugh R.

Affiliation

Leonard MO; Department of Medicine and Therapeutics, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

J Am Soc Nephrol ; 13(6): 1657-62, 2002 Jun.

Article in En | MEDLINE | ID: mdl-12039996

Subject(s)

Acute Kidney Injury/prevention & control; DNA-Binding Proteins; Hydroxyeicosatetraenoic Acids/therapeutic use; Ischemia/drug therapy; Kidney/blood supply; Lipoxins; Repressor Proteins; Trans-Activators; Alkyl and Aryl Transferases/genetics; Animals; Carrier Proteins/genetics; Intercellular Adhesion Molecule-1/genetics; Interleukin-1/genetics; Interleukin-6/genetics; Mice; Neutrophils/drug effects; Neutrophils/physiology; Proteins/genetics; RNA, Messenger/analysis; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Vascular Cell Adhesion Molecule-1/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Trans-Activators / Hydroxyeicosatetraenoic Acids / Lipoxins / DNA-Binding Proteins / Acute Kidney Injury / Ischemia / Kidney Limits: Animals Language: En Journal: J Am Soc Nephrol Journal subject: NEFROLOGIA Year: 2002 Document type: Article Affiliation country: Ireland Country of publication: United States

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