Serine 577 is phosphorylated and negatively affects the tRNA binding and eIF2alpha kinase activities of GCN2.

Garcia-Barrio, Minerva; Dong, Jinsheng; Cherkasova, Vera A; Zhang, Xiaolong; Zhang, Fan; Ufano, Sandra; Lai, Ruby; Qin, Jun; Hinnebusch, Alan G

Garcia-Barrio, Minerva; Dong, Jinsheng; Cherkasova, Vera A; Zhang, Xiaolong; Zhang, Fan; Ufano, Sandra; Lai, Ruby; Qin, Jun; Hinnebusch, Alan G.

Affiliation

Garcia-Barrio M; Laboratory of Gene Regulation and Development, NICHD/National Institutes of Health, Building 6A, Rm. B1A13, Bethesda, MD 20892, USA.

J Biol Chem ; 277(34): 30675-83, 2002 Aug 23.

Article in En | MEDLINE | ID: mdl-12070158

Subject(s)

Protein Kinases/chemistry; RNA, Transfer/metabolism; Saccharomyces cerevisiae/metabolism; eIF-2 Kinase/metabolism; Mass Spectrometry; Phosphorylation; Protein Kinases/metabolism; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae Proteins; Serine/metabolism; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Saccharomyces cerevisiae / RNA, Transfer / EIF-2 Kinase Language: En Journal: J Biol Chem Year: 2002 Document type: Article Affiliation country: United States Country of publication: United States

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