Chromatin structural analyses of the mouse Igkappa gene locus reveal new hypersensitive sites specifying a transcriptional silencer and enhancer.

Liu, Zhi-Mei; George-Raizen, Julia B; Li, Shuyu; Meyers, Katherine C; Chang, Mee Young; Garrard, William T

Liu, Zhi-Mei; George-Raizen, Julia B; Li, Shuyu; Meyers, Katherine C; Chang, Mee Young; Garrard, William T.

Affiliation

Liu ZM; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9148, USA.

J Biol Chem ; 277(36): 32640-9, 2002 Sep 06.

Article in En | MEDLINE | ID: mdl-12080064

Subject(s)

Chromatin/chemistry; Enhancer Elements, Genetic; Gene Silencing; Immunoglobulin kappa-Chains/genetics; Transcription, Genetic; Animals; Base Sequence; Binding Sites; Cell Line; Chromatin/metabolism; Chromosomes, Artificial, Yeast; DNA/metabolism; Deoxyribonuclease I/metabolism; Luciferases/metabolism; Mice; Mice, Transgenic; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B/metabolism; Polymerase Chain Reaction; Sequence Homology, Nucleic Acid; Time Factors; Transcriptional Activation; Transfection; Transgenes

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Chromatin / Enhancer Elements, Genetic / Immunoglobulin kappa-Chains / Gene Silencing Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2002 Document type: Article Affiliation country: United States

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