18F-labeled difluoroestradiols: preparation and preclinical evaluation as estrogen receptor-binding radiopharmaceuticals.

Seimbille, Yann; Rousseau, Jacques; Bénard, François; Morin, Catherine; Ali, Hasrat; Avvakumov, George; Hammond, Geoffrey L; van Lier, Johan E

Seimbille, Yann; Rousseau, Jacques; Bénard, François; Morin, Catherine; Ali, Hasrat; Avvakumov, George; Hammond, Geoffrey L; van Lier, Johan E.

Affiliation

Seimbille Y; Department of Nuclear Medicine and Radiobiology, Faculty of Medicine, Sherbrooke PET Center, Université de Sherbrooke, Sherbrooke, Que., Canada J1H 5N4.

Steroids ; 67(9): 765-75, 2002 Aug.

Article in En | MEDLINE | ID: mdl-12123788

Subject(s)

Estradiol/analogs & derivatives; Estradiol/metabolism; Fluorine Radioisotopes; Radiopharmaceuticals/metabolism; Receptors, Estrogen/metabolism; Animals; Breast Neoplasms/diagnostic imaging; Estradiol/chemical synthesis; Estradiol/chemistry; Female; Humans; Isotope Labeling; Radiopharmaceuticals/chemical synthesis; Radiopharmaceuticals/chemistry; Rats; Rats, Sprague-Dawley; Sex Hormone-Binding Globulin/metabolism; Thermodynamics; Tomography, Emission-Computed/methods; alpha-Fetoproteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Fluorine Radioisotopes / Receptors, Estrogen / Radiopharmaceuticals / Estradiol Type of study: Evaluation_studies Limits: Animals / Female / Humans Language: En Journal: Steroids Year: 2002 Document type: Article Country of publication: United States

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