Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors.

Oscier, David G; Gardiner, Anne C; Mould, Sarah J; Glide, Sharron; Davis, Zadie A; Ibbotson, Rachel E; Corcoran, Martin M; Chapman, Robert M; Thomas, Peter W; Copplestone, J Adrian; Orchard, Jenny A; Hamblin, Terry J

Oscier, David G; Gardiner, Anne C; Mould, Sarah J; Glide, Sharron; Davis, Zadie A; Ibbotson, Rachel E; Corcoran, Martin M; Chapman, Robert M; Thomas, Peter W; Copplestone, J Adrian; Orchard, Jenny A; Hamblin, Terry J.

Affiliation

Oscier DG; Department of Haematology, Royal Bournemouth Hospital, Bournemouth, United Kingdom. david.oscier@lineone.net

Blood ; 100(4): 1177-84, 2002 Aug 15.

Article in En | MEDLINE | ID: mdl-12149195

Subject(s)

Antigens, CD; Genes, p53/genetics; Immunoglobulin Heavy Chains/genetics; Immunoglobulin Variable Region/genetics; Leukemia, Lymphocytic, Chronic, B-Cell/genetics; Mutation; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Analysis of Variance; Antigens, Differentiation/analysis; Blotting, Southern; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 13; Female; Gene Deletion; Humans; Leukemia, Lymphocytic, Chronic, B-Cell/immunology; Leukemia, Lymphocytic, Chronic, B-Cell/mortality; Male; Membrane Glycoproteins; NAD+ Nucleosidase/analysis; Prognosis; Proportional Hazards Models; Sex Characteristics; Survival Rate; Trisomy

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin Variable Region / Leukemia, Lymphocytic, Chronic, B-Cell / Antigens, CD / Genes, p53 / Immunoglobulin Heavy Chains / Mutation Type of study: Prognostic_studies Limits: Female / Humans / Male Language: En Journal: Blood Year: 2002 Document type: Article Affiliation country: United kingdom Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links